The primary structure of the rat insulin-like growth factor II gene region |
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| Authors: | K Ikejiri T Ueno T Matsuguchi K Takahashi H Endo M Yamamoto |
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| Affiliation: | Department of Biochemistry, Kyushu University, Fukuoka, Japan. |
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| Abstract: | Complete nucleotide sequences of the rat insulin-like growth factor II gene region including 5' 18 kilobases (kb) up to the insulin gene, all exonic and intronic, and 3' 6 kb sequences were determined. Among these sequences several repetitive stretches became evident besides integration of type II Alu and identifier sequences. They were: (1) twelve repetitions of about 100 base pair (bp) units; (2) duplication of 60 bp units; (3) triplication of a 24 bp unit; and (4) 41-fold expansion of 12-15 bp units. |
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