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番茄红素调控肠道菌群对健康影响的研究进展
引用本文:施淑怡,崔海滨,冀星宇,申素霞,张燕,陈芳. 番茄红素调控肠道菌群对健康影响的研究进展[J]. 微生物学报, 2023, 63(7): 2563-2572
作者姓名:施淑怡  崔海滨  冀星宇  申素霞  张燕  陈芳
作者单位:中国农业大学食品科学与营养工程学院, 北京 100083;国家果蔬加工工程技术研究中心, 北京 100083;中粮屯河番茄有限公司, 新疆 乌鲁木齐 830099
基金项目:2021–2022昌吉州庭州创新团队项目(2021CT09)
摘    要:番茄红素(lycopene)在番茄中含量丰富,具有多种功能活性和营养价值,探讨番茄红素调控肠道菌群对健康的影响有助于深入理解番茄红素的健康效应和作用机制。本文综述了番茄红素的理化性质及其消化、吸收、代谢,重点阐述了番茄红素对宿主肠道菌群种类、数量和代谢产物的影响,以及在番茄红素调控作用下肠道菌群对宿主炎症、心血管疾病、非酒精性脂肪肝和癌症发展的干预作用。该综述为未来番茄营养探索及产品开发提供了思路和方向。

关 键 词:番茄红素  肠道菌群  干预  健康
收稿时间:2022-10-29
修稿时间:2023-02-02

Health-enhancing effect of lycopene based on the regulation of intestinal microbiota
SHI Shuyi,CUI Haibin,JI Xingyu,SHEN Suxi,ZHANG Yan,CHEN Fang. Health-enhancing effect of lycopene based on the regulation of intestinal microbiota[J]. Acta microbiologica Sinica, 2023, 63(7): 2563-2572
Authors:SHI Shuyi  CUI Haibin  JI Xingyu  SHEN Suxi  ZHANG Yan  CHEN Fang
Affiliation:College of Food Science & Nutritional Engineering, China Agricultural University, Beijing 100083, China;National Engineering Research Center for Fruits and Vegetables Processing, Beijing 100083, China;COFCO Tunhe Tomato Co., Ltd., Urumqi 830099, Xinjiang, China
Abstract:Lycopene, which is rich in tomatoes, has diverse functions and high nutritional value. Thus, it is of great significance to explore the health-enhancing effect of lycopene through intestinal microbiota and its mechanism. In this review, we summarized the physicochemical properties, digestion, absorption, and metabolism of lycopene, and particularly the influence of lycopene on the types, quantity, and metabolites of gut microbiota in the host. Furthermore, we discussed the intervention of gut microbiota in host inflammation, cardiovascular diseases, non-alcoholic fatty liver disease, and cancer development under the regulation of lycopene. This review may provide ideas and directions for the future exploration of tomato nutrition and product development.
Keywords:lycopene  gut microbiota  intervention  health
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