Mechanism of action of antimutagens. I. ionol modification of aberrations induced by different factors]

The capacity of decreasing the frequency of chromosome aberrations, spontaneous and induced by ionizing radiation (gamma-rays) and alkylating compounds (ethylene imine) was established to be inherent in ionole (2,6-di-tretbutyl-4-methylphenole). Crepis capillaris was used as the experimental material. Ionole was particularly efficient with respect to aberrations induced by ethylene imine. The decrease of the frequency of spontaneous and induced aberrations did not affect their spectrum.