Sonochemically fabricated enzyme microelectrode arrays for the environmental monitoring of pesticides |
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Authors: | Pritchard Jeanette Law Karen Vakurov Alexander Millner Paul Higson Séamus P J |
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Institution: | Gwent Electronic Materials, Monmouth House, Mamhilad Park, Pontypool NP4 OHZ, UK. |
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Abstract: | This paper describes the development of a novel sonochemically fabricated microelectrode based acetylcholinesterase and polyaniline carbon/cobalt phthalocyanine biosensor for the ultra-sensitive determination of pesticides. Arrays of this type are fabricated using microelectrode templates with population densities of 2 x 10(5) cm(-2). The enzymatic response of the sensors is inhibited upon incubation with the pesticide and in this report it is shown that paraoxon may be determined down to concentrations of 1 x 10(-17) M. This sensitivity has thus far not been achieved and mechanisms accounting for the enhancement of the sensitivity reported here are discussed. |
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