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Resistance of Thiobacillus novellus to mitomycin C and rifampicin.
Authors:C T Chow
Abstract:Thiobacillus novellus is highly resistant to mitomycin C and rifampicin. This resistance is not due to insusceptibility of the target molecules to the drugs, since mitomycin C cross-links the DNA and rifampicin inhibits the DNA-dependent RNA polymerase of T. novellus in vitro.
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