What is the ultimate fate of superoxide anion in vivo? |
| |
Authors: | Françoise Auchère Frank Rusnak |
| |
Institution: | Section of Hematology Research and the Department of Biochemistry & Molecular Biology, Mayo Clinic & Foundation, 200 First Street S.W., Rochester, MN 55905, USA. |
| |
Abstract: | For three decades, oxidative stress and the role of reactive oxygen species in biology have been extensively studied. Recently, a new interest in these areas has emerged with the discovery of superoxide reductases, a family of familiar bacterial metalloenzymes whose heretofore unknown function has now been apparently revealed. In a series of experiments utilizing genetic, molecular biological, and biochemical methods, these enzymes have been shown to be physiologically competent at removing superoxide. The role of these enzymes and their biological relationship to the well-known superoxide dismutases is discussed. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|