Replication factors license exonuclease I in mismatch repair |
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| Authors: | Surtees Jennifer A Alani Eric |
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| Institution: | Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA. |
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| Abstract: | A key question in the eukaryotic mismatch repair field is how strand excision is coordinated with mismatch recognition. In a recent issue of Molecular Cell, Dzantiev et al. present evidence that the replication factors PCNA and RFC modulate the directionality of EXOI-mediated excision. |
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