Department of Virology and Epidemiology, Baylor College of Medicine, Houston, Texas 77025 USA
Abstract:
Two fucose-containing lipids with long chain base as their apolar moiety are described. These compounds were shown to possess a free amino group and a net positive charge by derivatization with specific amino reagents and by cation exchange column chromatography. The presence of long chain base was demonstrated by periodate-NaB3H]4 treatment to yield long chain alcohol and by 3H]-dansylation followed by hydrolysis to yield dansyl-long chain base.