Plasma growth hormone and thyrotropin responses to thyrotropin releasing hormone in freely behaving and urethane anesthetized rats. |
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| Authors: | I Wakabayashi M Kanda N Miki R Demura K Shizume |
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| Institution: | Department of Medicine Tokyo Women''s Medical College 10-Kawadacho, Ichigaya, Shinjuku-ku, Tokyo, Japan 162 |
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| Abstract: | Plasma GH and TSH responses to thyrotropin releasing hormone (TRH) were examined in freely behaving and urethane anesthetized rats. The i.v. administration of TRH (200ng/100g b.wt.) resulted in consistent elevations of plasma GH only in urethane anesthetized rats, while significant elevations of plasma TSH were similarly observed in both conditions. Results suggest that urethane influences plasma GH responses to TRH. |
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