Human functional genetic studies are biased against the medically most relevant primate-specific genes |
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Authors: | Lili Hao Xiaomeng Ge Haolei Wan Songnian Hu Martin J Lercher Jun Yu Wei-Hua Chen |
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Affiliation: | 1.CAS Key Laboratory of Genome Sciences and Information,Beijing Institute of Genomics, Chinese Academy of Sciences,Beijing,China;2.Graduate University of Chinese Academy of Sciences,Beijing,China;3.Bioinformatics group,Heinrich-Heine University Düsseldorf,Germany;4.European Molecular Biology Laboratory (EMBL),Heidelberg,Germany |
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Abstract: | Background Many functional, structural and evolutionary features of human genes have been observed to correlate with expression breadth and/or gene age. Here, we systematically explore these correlations. |
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