A new solid-phase support for oligonucleotide synthesis. |
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| Authors: | R V Devivar S L Koontz W J Peltier J E Pearson T A Guillory J D Fabricant |
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| Institution: | FlowGenix Corporation, Webster, TX 77598, USA. |
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| Abstract: | An alternative solid support for oligonucleotide synthesis was developed by coupling a polymer colloid to a modified polyethylene filter disc. The functions on the polymer colloid not used for attachment to the surface were derivatized with a Jeffamine diamine and loaded with appropriate deoxynucleoside succinates. The performance of this support system was evaluated and compared to existing resins. |
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