| IL-33／ST2信号通路在疾病中作用的研究进展 |
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| 引用本文： | 曹梦远,徐永妮,叶伟,张芳琳.IL-33／ST2信号通路在疾病中作用的研究进展[J].微生物学免疫学进展,2013(6):71-75. |
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| 作者姓名： | 曹梦远 徐永妮 叶伟 张芳琳 |
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| 作者单位： | [1]第四军医大学微生物学教研室,西安710032 [2]解放军第323医院,西安710054 |
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| 基金项目： | 国家自然科学基金资助项目（30972590,30970148） |
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| 摘 要： | IL-33是在2005年发现的一个多功能细胞因子，属于IL-1家族新成员。IL-33通过受体ST2活化NF-KB和MAPK信号通路，促进Th2细胞因子的产生，在多种疾病的发生发展过程中起着重要的作用。
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| 关 键 词： | IL-33 ST2 疾病 |
Advances in the role of IL-33/ST2 singling pathway in the disease |
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| CAO Meng-yuan,XU Yong-ni,YE Wei,ZHANG Fang-lin.Advances in the role of IL-33/ST2 singling pathway in the disease[J].Progress In Microbiology and Immunology,2013(6):71-75. |
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| Authors: | CAO Meng-yuan XU Yong-ni YE Wei ZHANG Fang-lin |
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| Institution: | ( Department of Microbiology,Fourth Military Medical University,Xi＇ an 710032, China) |
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| Abstract: | IL-33 is a muhifunctional cytokine discovered in 2005, which belongs to the new members of the IL-1 family. Through its receptor ST2, IL-33 activates NF-KB and MAPK signaling pathway, promotes production of Th2 cytokines and olavs an important role in the occurrence as well as the development of many diseases. |
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| Keywords: | IL-33 ST2 Diseases |
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