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Structure of the vanadate-induced crystals of sarcoplasmic reticulum Ca2+-ATPase
Authors:K Taylor  L Dux  A Martonosi
Institution:Anatomy Department, Duke University Medical Center P.O. Box 3011, Durham, N.C. 27710, U.S.A.;Institute of Biochemistry, School of Medicine University of Szeged, Hungary;Department of Biochemistry, State University of New York Upstate Medical Center, Syracuse, N.Y. 13210, U.S.A.
Abstract:The projected structure of the vanadate-induced crystalline aggregates of Ca2+-ATPase molecules in isolated sarcoplasmic reticulum membranes has been determined. The molecules form tubular crystals with an oblique surface lattice having cell dimensions a = 65.9 A, b = 114.4 A and gamma = 77.9 degrees. The space group is P2. The crystalline tubules are formed through lateral aggregation of chains made up of dimers of Ca2+-ATPase molecules.
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