Glycerol-Furcated Oligonucleotides: Synthesis and Aggregation |
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| Authors: | H Rosemeyer E Feiling Wolfgang Nierling F Seela |
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| Institution: | 1. Laboratorium für Organische und Bioorganische Chemie;2. Physikalische Chemie, Institut für Chemie, Universit?t Osnabrück , Barbarastr. 7, D-49069, Osnabrück, Germany |
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| Abstract: | Abstract The synthesis of the bi-furcated complementary oligonucleotides 2 and 3 is described and their complex formation is studied as a function of their molar ratio and ionic strength by means of temperature-dependent UV- and CD spectroscopy as well as by dynamic light scattering. Structural proposals for the different aggregates are given. |
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