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Zn2+ Promoted Hydrolysis of RNA |
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| Authors: | Satu Mikkola Izabela Zagorowska Harri Lönnberg |
| Institution: | Department of Chemistry , University of Turku , FIN-20014, Turku, Finland |
| Abstract: | Abstract The Zn2+ promoted hydrolysis of phosphodiester bonds of RNA has been studied by using a series of model compounds from dinucleoside monophosphates to oligo- and polynucleotides. The results will be discussed with respect to complex formation between the metal ion catalysts and substrates. |
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