Disaccharide Nucleosides And Their Enzymatic And Chemical Incorporation Into Oligonucleotides |
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| Authors: | Ekaterina V. Efimtseva Lubov S. Victorova Andrei A. Rodionov Boris S. Ermolinsky Marina V. Fomitcheva Vera L. Tunitskaya |
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| Affiliation: | Engelhardt Institute of Molecular Biology, Russian Academy of Sciences , Vavilov str. 32, Moscow , 117984 , Russia |
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| Abstract: | Abstract A high yield synthesis of different O-ribofuranosylnucleosides has been achieved. Kinetics of the acid-catalysed hydrolysis of disaccharide nucleosides has been studied. Chemical and enzymatic incorporation of 2′-O-ribofuranosyl-nucleoside residue into oligonucleotides was investigated. |
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