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Protein and RNA of Human Telomerase as Targets for Modified Oligonucleotides |
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| Authors: | M von Janta-lipinski K Gaertner C Lehmann H Scheer J Schildt E Matthes |
| Institution: | Max-Delbrück-Center for Molecular Medicine , Robert-R?ssle-Str, 10 D-13122, Berlin, Germany |
| Abstract: | Abstract Chimeric oligodeoxynucleotides containing phosphorothioate and N3′→P5′phosphoramidate linkages were synthesized. These oligomers show a high inhibitory activity against human telomerase. |
| Keywords: | |