Pna Array Technology in Molecular Diagnostics |
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Authors: | Albert Geiger Ane Lester Jörg Kleiber Henrik Ørum |
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Affiliation: | 1. PNA Diagnostics A/S , Ronnegade 2, DK-21OO , Copenhagen ? , Denmark;2. Boehringer Mannheim GmbH, Molecular Diagnostics , D-82377 , Penzberg , Germany |
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Abstract: | Abstract A comparative study using immobilised DNA and PNA oligomers demonstrates the suitability of PNA molecules as sequence specific capture probes in the detection of single point mutations in a DNA analyte and in the analysis of complex analyte mixtures. |
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