Gamma-crystallin genes in carp: cloning and characterization. |
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| Authors: | T Chang C L Lin P H Chen W C Chang |
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| Institution: | Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan, R.O.C. |
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| Abstract: | The carp gamma-crystallin gene family was found to be composed of at least three members: gamma m1, gamma m2 and gamma m3. The encoded products are very similar to other known gamma-crystallins but with their own peculiarities: (1) they all have a high methionine content: 12.4%, 14% and 8.4% in gamma m1, gamma m2 and gamma m3, respectively; and (2) the amino acid sequences are aberrant in the region before connecting peptides and its corresponding region in motif 4. Their protein structures might remain the same as those of other gamma-crystallins since they retain all the conserved amino acid residues essential for maintaining the loops in the protein structures. |
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