| 暴露于高压氧时大鼠纹状体和下丘脑内L—Enk含量的变化 |
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| 引用本文： | 练庆林 倪国坛. 暴露于高压氧时大鼠纹状体和下丘脑内L—Enk含量的变化[J]. 生理学报, 1993, 45(2): 182-185 |
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| 作者姓名： | 练庆林 倪国坛 |
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| 作者单位： | 第二军医大学海医系潜水生理学教研室，第二军医大学海医系潜水生理学教研室，第二军医大学海医系潜水生理学教研室，第二军医大学海医系潜水生理学教研室，第二军医大学海医系潜水生理学教研室，第二军医大学海医系潜水生理学教研室 上海 200433，上海 200433，上海 200433，上海 200433，上海 200433，上海 200433 |
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| 基金项目： | 国家自然科学基金(No.38970319) |
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| 摘 要： | 本研究目的在于探讨大鼠氧惊厥时,纹状体和下丘脑内亮-脑啡肽(L-Enk)含量的变化。实验中将32只雄性大鼠随机分为4组:常压空气组、高压常氧氮组、高压氧未惊厥组和高压氧惊厥组。用放射免疫法测定了纹状体和下丘脑内L-Enk含量。结果显示,在高压氧环境中暴露的大鼠纹状体和下丘脑内L-Enk含量明显高于常压空气组和高压常氧氮组;且增高到一定水平时发生惊厥。实验结果提示,动物惊厥与纹状体和下丘脑中L-Enk含量的增加呈正相关,而与高压氧环境及加减压方式无显著关系。
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| 关 键 词： | 脑啡肽 高压氧 下丘脑 |
CHANGES OF LEU-ENKEPHALIN IN STRIATUM AND HYPOTHALAMUS OF RATS DURING HYPERBARIC OXYGEN EXPOSURE |
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| LIAN QING-LIN,NI GUO-TAN,CHENG TAO,TAO HENG-YI,HANG RONG-CHUN,QIAN BING-RONG. CHANGES OF LEU-ENKEPHALIN IN STRIATUM AND HYPOTHALAMUS OF RATS DURING HYPERBARIC OXYGEN EXPOSURE[J]. Acta Physiologica Sinica, 1993, 45(2): 182-185 |
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| Authors: | LIAN QING-LIN NI GUO-TAN CHENG TAO TAO HENG-YI HANG RONG-CHUN QIAN BING-RONG |
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| Affiliation: | LIAN QING-LIN,NI GUO-TAN,CHENG TAO,TAO HENG-YI,HANG RONG-CHUN,QIAN BING-RONG Department of Diring Physiology,Iaeully of Xaral Medieire Secoud Mititmy Medical Emnrsity,Shanghai 200433 |
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| Abstract: | The purpose of this study is to investigate the changes of Leu--Enkephalin (L-Enk)content in striatum and hypothalamus of rats during hyperbaric (HBO) oxygenexposure. Thirty--two male rats in the experiment were randomly divided into fourgroups: normobaric air group. normoxic hyperbaric nitrox group, nonconvulsionHBO group and convulsion HBO group. L--Enk content in striatum and hypothalamuswas determined by radioimmunoassay. The results show that L-Enk content in thestriatum and hypothalamus of rats exposed to hyperbaric oxygen environment weremarkedly higher than that of rats exposed to normobaric air and normoxic hyperbaricnitrox. The experimental results suggest that the elevation of L--Enk content in stria-tum and hypothalamus shows a positive relationship with thc HBO exposure durationof animals and that there was no marked relationship with normoxic hyperbaric nitroxenvironment and compression--decompression method. |
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| Keywords: | enkephalin hyperbaric oxygen oxygen convulsion |
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