Histamine: Its metabolism and localization in mammary gland |
| |
| Institution: | 1. Department of Biogenic Amines, Polish Academy of Sciences, Tylna 3, PL 90-950 Lodz, Poland;2. Department of Anatomy, University of Helsinki, Siltavuorenpenger 20, SF-00170 Helsinki, Finland;1. Division of Allergy and Clinical Immunology, University of Virginia, Charlottesville, Va;2. Allergy Partners of Fredericksburg, Fredericksburg, Va;3. Division of Rheumatology, Allergy and Immunology, University of North Carolina, Chapel Hill, NC;1. University of La Rochelle, LaSIE UMR 7356 CNRS, France;2. Institut de Recherche des Sciences et Techniques de la Ville, France;3. École Nationale Supérieure d’Architecture de Nantes, CERMA UMR 1563, France;1. Collaborative Innovation Center of Chemical Science and Engineering, Tianjin 300072, China;2. Key Laboratory for Green Chemical Technology of Ministry of Education, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China;1. Translational Research in Pediatric Specialities Area, Allergy Unit, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy;2. Department of Pediatrics, Albert Einstein College of Medicine and the Children’s Hospital at Montefiore, Bronx, NY |
| |
| Abstract: | 1. Mammary gland of mouse (Mus musculus), rat (Rattus rattus), guinea pig (Cavia porcellus), cow (Bos taurus) and pig (Sus scrofa) contains different but always high concentrations of histamine.2. Generally, the tissue histamine is localized in mast cells, although non-mast cell histamine immuno-reactivity is also present in mammary glands of the mouse, cow and pig. No histamine immunoreactive nerves could be detected.3. Mammary glands are able to synthesize and inactivate histamine; the activity of specific histidine decarboxylase and at least one of the catabolizing enzyme could be demonstrated.4. Histamine fulfils basic criteria for being involved in physiological function of mammary glands. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
