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A comparison of serum retinol concentration between human and different species of normo and hypercholesterolemic nonhuman primates fed semi-purified diets with defined amounts of vitamin A
Institution:1. Regional Institute for Population Studies (RIPS), University of Ghana, Legon-Accra, Accra, Ghana;2. School of Dietetics and Human, Nutrition McGill University, Ste Anne de Bellevue, QC Canada;3. Department of Nutrition and Food Science, University of Ghana, Legon-Accra, Accra, Ghana;4. Nutrition Division, Food and Agriculture Organization of the United Nations, Rome, Italy;5. Nursing Research Centre of the Jewish General Hospital, affiliated with McGill University, Ste Anne de Bellevue, QC Canada;1. Department of Biochemistry, College of Agricultural and Life Sciences, University of Wisconsin-Madison, 433 Babcock Drive, Madison, WI 53706, United States;2. Department of Animal Sciences, University of Florida, Gainesville, FL 32611, United States;3. Rheumatic and Autoimmune Diseases, Center for Immunology, Department of Medicine, University of Minnesota, Minneapolis, MN 55455, United States;4. Rhapsody Data, LLC, Madison, WI 53705, United States
Abstract:
  • 1.1. Serum retinol and total cholesterol concentrations were determined in several species of nonhuman primates fed semipurified diets. Two species of Old World and three species of New World nonhuman primates were examined.
  • 2.2. Retinol levels were significantly lower (up to four-fold) in the serum of the smaller New World than the larger Old World animals and the difference could not be explained by differences in dietary make-up.
  • 3.3. Cholesterol levels were not different between the groups but differed within a species when type of dietary fat was altered.
  • 4.4. Differences in circulating levels of retinol may reflect differences in levels of retinol binding protein between the groups.
Keywords:
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