Hair fibre progenitor cells: developmental status and interactive potential |
| |
| Institution: | 1. Chongqing Luneng Development (Group) Co. LMD, 777 Luneng Xingcheng, Yubei District, Yulu avenue, Chongqing, 400000, China;2. Laboratory for Track Engineering and Operations for Future Uncertainties (TOFU Lab), Department of Civil Engineering, School of Engineering, The University of Birmingham, Edgbaston, B15 2TT, Birmingham, United Kingdom;1. Al Imam Muhammad Ibn Saud Islamic University, Department of Dermatology, Riyadh, Saudi Arabia;2. Department of Dermatology, Medical University of Warsaw, Warsaw, Poland;3. Department of Neuropeptides, Mossakowski Medical Research Centre, Warsaw, Poland;4. Department of Dermatology and Skin Sciences, University of British Columbia, Vancouver, British Columbia, Canada;5. Department of Dermatology, New York University Langone Medical Center, New York, New York;1. Programa de Pós-Graduação em Física, Campus Prof. José Aloísio de Campos, UFS, 49100-000 São Cristóvão, SE, Brazil;2. Centro Brasileiro de Pesquisas Físicas (CBPF), 22290-180 Rio de Janeiro, RJ, Brazil;3. Departamento de Física, Campus Prof. Alberto Carvalho, UFS, 49506-036 Itabaiana, SE, Brazil;4. Centro de Ciências Naturais e Humanas (CCNH), Universidade Federal do ABC (UFABC), 09210-170 Santo André, SP, Brazil |
| |
| Abstract: | The plurality of function and complex differentiation of hair follicle epidermis means that this tissue may have more than one stem cell location. Progenitor cells isolated from the extreme base of the hair follicle, have been shown to have original and highly specialized properties by their morphology and behaviour in vitro, and their capacity to influence dermal differentiation. We have questioned whether production of six or seven distinct epidermal cell types comes from a single progenitor stock. As an alternative we suggest a division of the productive load, where the sources of the inner root sheath and fibre differ, and their composite populations may represent different stages in the same cell lineage, rather than totally separate differentiation states. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
