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In vivo evaluation of 5-hydroxytryptamine stimulation of the testes in the fiddler crab,Uca pugilator: A presumed action on the neuroendocrine system
Institution:1. College of Life Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China;2. Gutian Edible Fungi Research Institute, Fujian Agriculture and Forestry University, Gutian, Fujian, China
Abstract:1. Male fiddler crabs, Uca pugilator, received injections of 5-hydroxytryptamine (5-HT, serotonin). The crabs showed dose-dependent testicular development.2. Like 5-HT, the 5-HT releaser fenfluramine and the 5-HT potentiator fluoxetine induced testicular maturation also, but the 5-HT receptor blocker LY-53857 did not.3. The data support the hypothesis that 5-HT exerts this stimulatory effect on the testes indirectly, by triggering release of gonad-stimulating hormone.
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