Taurine regulation of Ca2+ uptake and (Ca2+ + Mg2+)-ATPase in developing chick B-cells |
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Affiliation: | 2. INRAE, Université de Tours, BOA, 37380, Nouzilly, France;2. Department of Animal and Avian Sciences, University of Maryland, College Park, MD, USA;3. Department of Agricultural, Food, and Nutritional Science, University of Alberta, Edmonton, AB, Canada |
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Abstract: | - 1.1. The objective of the present study was to determine the effect of age and taurine on chick B cell calcium uptake and membrane (Ca2+ + Mg2+)-ATPase activity in 1–4-week-old chicks.
- 2.2. The calcium uptake rate decreased with age (P < 0.05) and was further decreased by taurine (P < 0.05).
- 3.3. (Ca2+ + Mg2+)-ATPase activity increased with age (P < 0.05) and was stimulated by taurine (P < 0.05).
- 4.4. The data demonstrate that the flux of calcium across the B-cell membrane changes during early post-hatch development, and that taurine regulates both the influx and efflux of calcium in chick B-cells.
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