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Novel cassane diterpenes from the seeds of Caesalpinia minax
Authors:Guoxu Ma  Jingquan Yuan  Haifeng Wu  Kan Fang  Junshan Yang  Liyan Ma  Xudong Xu
Affiliation:1. Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100193, China;2. Guangxi Botanical Garden of Medical Plant, Nanning 530023, China;3. Anhui University of Traditional Chinese Medicine, Hefei 230038, China
Abstract:Three new cassane diterpenes, sucutiniranes G (1), H (2) and I (3) were isolated from the seeds of Caesalpinia minax Hance. Their structures were elucidated by various spectroscopic techniques (UV, IR, MS, CD, 1D and 2D NMR). All compounds were evaluated for cytotoxic activities against MCF-7 and HepG-2 human cancer cell lines.
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