Secondary metabolites from the liverwort Heteroscyphus coalitus |
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Authors: | Zhao-Min Lin Li-Ning Wang Dong-Xiao Guo Xiao-Ning Wang Yong-Qing Liu Jin-Chuan Zhou Hong-Xiang Lou |
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Affiliation: | Department of Natural Products Chemistry, School of Pharmaceutical Sciences, Shandong University, No. 44 West Wenhua Road, Jinan 250012, PR China |
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Abstract: | A new dihydroisocoumarin derivative, R-(?)-heteroscyphide (1), together with three known terpenoid derivatives (2–4), were isolated from the liverwort Heteroscyphus coalitus. Their structures were elucidated by spectroscopic methods and the biogenetic pathway of compound 1 was proposed. Cytotoxic test revealed that they exhibited moderate inhibitory activity to three human tumor cell lines. |
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