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Two new compounds from Trigonostemon heterophyllus
Authors:Yi-Xing Li  Wen-Li Mei  Wen-Jian Zuo  You-Xing Zhao  Wen-Hua Dong  Hao-Fu Dai
Institution:1. Hainan Key Laboratory for Research and Development of Tropical Natural Products, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, Hainan, PR China;2. Hainan Key Laboratory for Research and Development of Natural Product from Li Folk Medicine, Haikou 571101, Hainan, PR China;3. College of Agriculture, Hainan University, Haikou 570228, Hainan, PR China
Abstract:Phytochemical investigation on the stems of Trigonostemon heterophyllus led to the isolation of a new diterpene, trigonoheterene (1), and a new naphthoquinone, trigonoheterone (2), together with two known compounds, 3,4-seco-sonderianol, (3) and trigonochinene E, (4). Their structures were determined by spectroscopic techniques (UV, IR, MS, 1D and 2D NMR). All compounds were evaluated for cytotoxic activities and antibacterial activities.
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