A dimeric chromanone and a phthalide: Metabolites from the seagrass-derived fungus Bipolaris sp. PSU-ES64 |
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Authors: | Jiraporn Arunpanichlert Vatcharin Rukachaisirikul Kwanruthai Tadpetch Souwalak Phongpaichit Nongporn Hutadilok-Towatana Orathai Supaphon Jariya Sakayaroj |
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Institution: | 1. Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Prince of Songkla University, Hat Yai, Songkhla 90112, Thailand;2. Natural Products Research Center and Department of Microbiology, Faculty of Science, Prince of Songkla University, Hat Yai, Songkhla 90112, Thailand;3. Department of Biochemistry, Faculty of Science, Prince of Songkla University, Hat Yai, Songkhla 90112, Thailand;4. National Center for Genetic Engineering and Biotechnology (BIOTEC), Thailand Science Park, Klong Luang, Pathumthani 12120, Thailand |
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Abstract: | Two new metabolites, a dimeric chromanone, bipolarinone (1), and a phthalide, bipolarilide (2), as well as eight known compounds have been isolated from the seagrass-derived fungus Bipolaris sp. PSU-ES64. The structures were elucidated by analysis of spectroscopic data. The absolute configuration of 1 was determined by circular dichroism spectroscopy, Mosher's method, and NOEDIFF data. The antioxidant and antimicrobial activities of the isolated compounds were examined. |
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