| 蛋白磷酸酶抑制剂变构霉素的生物合成及其抑制位点研究 |
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| 引用本文： | 柴小涛,陈小龙,郑裕国,沈寅初. 蛋白磷酸酶抑制剂变构霉素的生物合成及其抑制位点研究[J]. 微生物学通报, 2009, 36(10): 1587-1591 |
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| 作者姓名： | 柴小涛 陈小龙 郑裕国 沈寅初 |
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| 作者单位： | 浙江工业大学生物与环境工程学院,生物工程研究所,浙江,杭州,310014 |
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| 基金项目： | 浙江省科技厅重大专项(No. 2007C12088); 浙江省教育厅重点项目(No. 20060855) |
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| 摘 要： | 变构霉素具有很强的蛋白磷酸酶抑制作用和良好的抗菌活性, 尤其是对油菜菌核病的抑制作用。本文综述了近年来有关变构霉素生物合成和蛋白磷酸酶抑制位点方面的最新研究进展。
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| 关 键 词： | 蛋白磷酸酶 变构霉素 生物合成 抑制 |
Biosynthesis of Tautomycin and Its Inhibition Region of Protein Phosphatase |
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| CHAI Xiao-Tao,CHEN Xiao-Long,ZHENG Yu-Guo and SHEN Yin-Chu. Biosynthesis of Tautomycin and Its Inhibition Region of Protein Phosphatase[J]. Microbiology China, 2009, 36(10): 1587-1591 |
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| Authors: | CHAI Xiao-Tao CHEN Xiao-Long ZHENG Yu-Guo SHEN Yin-Chu |
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| Affiliation: | Institute of Bioengineering, Zhejiang University of Technology, Hangzhou, Zhejiang 310014, China;Institute of Bioengineering, Zhejiang University of Technology, Hangzhou, Zhejiang 310014, China;Institute of Bioengineering, Zhejiang University of Technology, Hangzhou, Zhejiang 310014, China;Institute of Bioengineering, Zhejiang University of Technology, Hangzhou, Zhejiang 310014, China |
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| Abstract: | Tautomycin is one of well-known specific protein phosphatase inhibitors and exhibiting potent antifungal ability, especially to Sclerotinia sclerotiolum. This article reviews the recent research progress of tautomycin, focusing on its inhibition region and biosynthesis. |
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| Keywords: | Protein phosphatase Tautomycin Biosynthesis Inhibition |
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