The levels of main urinary metabolite of prostaglandin F1α and F2α in human subjects measured by radioimmunoassay |
| |
| Authors: | Shiro Ohki Yoshimasa Nishigaki Katsuhiro Imaki Masayasu Kurono Fumio Hirata Toshio Hanyu Nobuhiko Nakazawa |
| |
| Affiliation: | Research Institute, Ono Pharmaceutical Co., Ltd. Sakurai, Shimamoto-Cho, Mishima-Gun, Osaka, Japan;Daiichi Radioisotope Lab., Ltd. 5-6-9, Narihira, Sumida-Ku, Tokyo, Japan |
| |
| Abstract: | Radioimmunoassay technique for measuring 5α,7α-dihydroxy-11-keto-tetranorprosta-1,16-dioic acid, the main urinary metabolite of PGF1α and PGF2α (PGF2α-MUM), was further improved.It was postulated based on some experimental data that the PGF2α-MUM exists in the urine mostly as dioic acid form, not as δ-lactone formThe daily excretion of PGF2α-MUM in men ranged from 14.43 μg to 36.14 μg and in women from 5.21 μg to 14.25 μg. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
