Compositional biases and polyalanine runs in humans |
| |
Authors: | Cocquet Julie De Baere Elfride Caburet Sandrine Veitia Reiner A |
| |
Affiliation: | INSERM E0021 and U361, Reproduction et Physiopathologie Obstétricale, Hôpital Cochin, 75014 Paris, France. |
| |
Abstract: | Human proteins containing polyalanine tracts tend to have runs of other amino acids and their open reading frames (ORFs) display a biased codon usage. Their alanine, glycine, proline, and histidine content strongly correlates with the GC content of the third codon base, suggesting that the compositional specificity of these proteins is dictated to a great extent by the evolution of their ORFs. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|