Effect of cocaine on the contractile response to noradrenaline in the epididymal and prostatic regions of the vas deferens |
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| Authors: | Berdysheva L V Kichikulova T P Manukhin B N |
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| Affiliation: | N. K. Koltsov Institute of Developmental Biology of the Russian Acad Sci., Moscow, Russia. |
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| Abstract: | In the prostatic half of the rat vas deferens, the response to noradrenaline under the cocaine effect revealed a phasic and a tonic components, whereas in the epididymal portion of the vas deferens there only occurred the tonic component. Cocaine increased the maximal tonic contractile response to noradrenaline in the epididymal portion and the maximal phasic response--in the prostatic one. Mechanisms of direct postsynaptic action of cocaine are discussed. |
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