Demonstration of cholera-like enterotoxin production by Campylobacter jejuni |
| |
| Authors: | Herman Goossens Jean-Paul Butzler Yoshifumi Takeda |
| |
| Affiliation: | Department of Microbiology, St. Pieters Hospital, Free University of Brussels, 322 Hoogstraat, B-1000 Brussels, Belgium;Department of Bacterial Infection, The Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, Minato-ku, Tokyo 108, Japan |
| |
| Abstract: | Abstract By means of a newly developed medium, cholera-like enterotoxin production by Campylobacter jejuni could be shown in 25 C. jejuni strains isolated from diarrheic cases. This new medium was found to yield a higher amount of enterotoxin than the two previously reported media for this purpose. Neutralization of the activity of the toxin to cause morphological changes of Chinese hamster ovary (CHO) cells by antisera against cholera toxin and heat-labile enterotoxins of Escherichia coli (LTh and LTp) was also demonstrated, indicating a close immunological relation of these toxins. |
| |
| Keywords: | Campylobacter jejuni cholera-like toxin CHO cell assay CT LTh LTp |
|
|
