The infectious hypoxia: occurrence and causes during Shigella infection |
| |
| Institution: | 1. Department of Enteric Infections, Bacterial Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, United States;2. Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States;3. LimmaTech Biologics AG, Schlieren, Switzerland;4. PATH, Washington, DC, United States;5. Naval Medical Research Center, Silver Spring, MD, United States;1. The First Clinical College of Lanzhou University, Lanzhou, China;2. Department of Cardiology, The First Hospital of Lanzhou University, Lanzhou, China;3. Yale School of Public Health, Yale University, USA;4. Fu Wai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China;1. Graduate School of Agriculture, Hokkaido University, Kita 9, Nishi 9, Kita-ku, Sapporo, Hokkaido 060-8589, Japan;2. Institute for Biological Problems of Cryolithozone, Siberian Branch, Russian Academy of Science, Yakutsk 677980, Russia;3. Melnikov Permafrost Institute, Russian Academy of Science, Yakutsk 677010, Russia |
| |
| Abstract: | Hypoxia is defined as a tissue oxygenation status below physiological needs. During Shigella infection, an infectious hypoxia is induced within foci of infection. In this review, we discuss how Shigella physiology and virulence are modulated and how the main recruited immune cells, the neutrophils, adapt to this environment. |
| |
| Keywords: | Infectious hypoxia Neutrophils |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
