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A point mutation in the amino terminus of TLR7 abolishes signaling without affecting ligand binding
Authors:Iavarone Carlo  Ramsauer Katrin  Kubarenko Andriy V  Debasitis Jason C  Leykin Igor  Weber Alexander N R  Siggs Owen M  Beutler Bruce  Zhang Pu  Otten Gillis  D'Oro Ugo  Valiante Nicholas M  Mbow M Lamine  Visintin Alberto
Affiliation:Immunology US, Novartis Vaccines and Diagnostics, Cambridge, MA 02139, USA.
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