Second Case of Histoplasmosis in a Captive Mara (<Emphasis Type="Italic">Dolichotis patagonum</Emphasis>): Pathological Findings |
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Authors: | A Pérez-Torres A Rosas-Rosas A Parás-García C Juan-Sallés M L Taylor |
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Institution: | (1) Department of Microbiología-Parasitología, Facultad de Medicina, Universidad Nacional Autónoma de México (UNAM), 04510 Mexico, DF, Mexico;(2) Department of Biología Celular-Tisular, Facultad de Medicina, Universidad Nacional Autónoma de México (UNAM), 04510 Mexico City, DF, Mexico;(3) Department of Animal Health, Africam Safari, 11 Oriente 2407 (Col. Azcárate), 72007 Puebla, PL, Mexico;(4) ConZOOlting Wildlife Management, La Canvella 1, Nau 1, 08445 Samalus, BCN, Spain |
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Abstract: | A second case of histoplasmosis in a captive mara (Dolichotis patagonum) from a colony at the wildlife park Africam Safari, Puebla, Mexico, is described, and the mara died with disseminated clinical
form of the disease, affecting mostly the large intestine and adrenal. The pathological findings of this case 2 revealed severe
granulomatous typhlocolitis and moderate granulomatous gastrohepatic lymphadenitis with numerous yeast-like cells, 2–4 μm
in diameter, with a clear halo surrounding them inside the cytoplasm of macrophages, suggesting the parasitic form of Histoplasma capsulatum. Adrenocortical cells had abundant similar microorganisms in their cytoplasm without any associated lesion. Gomori’s methenamine
silver and periodic acid Schiff stained positively these microorganisms. Immunohistochemistry, using a rabbit anti-H. capsulatum serum, and transmission electron microscopy supported the diagnosis of H. capsulatum infection. |
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Keywords: | Mara Histoplasmosis Outbreak Histopathological findings |
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