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Integrator: surprisingly diverse functions in gene expression
Affiliation:1. Department of Biochemistry and Molecular Biology, The University of Texas Medical School at Houston, Houston, TX 77030, USA;2. The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, TX 77030, USA;1. Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260, USA;1. Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK;2. Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, 1649-028 Lisboa, Portugal;3. Department of Biological Sciences, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, 226-8501Yokohama, Japan;1. Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK;1. The Francis Crick Institute, Mill Hill Laboratory, The Ridgeway, London NW7 1AA, UK;2. Center for Proteomics, Erasmus MC, Wytemaweg 80, 3015 CN Rotterdam, the Netherlands;1. Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136, USA;2. The Wistar Institute, Philadelphia, PA 19104, USA;3. Department of Biochemistry and Molecular Biology, The University of Texas Medical School at Houston, Houston, TX 77030, USA;4. The Fels Institute, Temple University School of Medicine, Philadelphia, PA 19140, USA;5. Stowers Institute for Medical Research, Kansas City, MO 64110, USA;6. Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, The Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA
Abstract:
Keywords:Integrator  UsnRNA processing  transcriptional activation  pause-release  RNAPII CTD
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