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Single-molecule insights into mRNA dynamics in neurons
Affiliation:1. Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA;2. Gruss Lipper Biophotonics Center, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA;3. Janelia Farm Research Campus, Howard Hughes Medical Institute, 19700 Helix Drive, Ashburn, VA 20147, USA;4. Department of Physics and Astronomy, Seoul National University, Seoul 151-747, Korea;5. Institute of Molecular Biology and Genetics, Seoul National University, Seoul 151-742, Korea;1. Department of Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, United Kingdom;2. Vision and Eye Research Unit (VERU), Postgraduate Medical Institute, Anglia Ruskin University, Eastings 204, East Road, Cambridge CB1 1PT, United Kingdom;1. Neuroscience Research Institute, Department of Molecular Cellular Developmental Biology, University of California, Santa Barbara, CA 93106, USA;1. Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, New York, NY 10461, USA;2. Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine, New York, NY 10461, USA;3. Momentum Laboratory of Molecular Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest 1051, Hungary;4. School of Ph.D. Studies, Semmelweis University, Budapest 1085, Hungary;1. Department of Anatomy, Brain Research Institute, and Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul 120-752, South Korea;2. Patrick Wild Centre, Centre for Integrative Physiology, Hugh Robson Building, University of Edinburgh, Edinburgh EH8 9XD, UK;3. Department of Biochemistry and Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada;4. Department of Physiology Development and Neuroscience, Anatomy Building, Downing Street, University of Cambridge, Cambridge CB2 3DY, UK
Abstract:
Keywords:RNA localization  mRNA tracking  local translation  smFISH
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