A Novel Approach for Studying Histone H1 Function in Vivo |
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| Authors: | Giorgia Siriaco Renate Deuring Gina D. Mawla John W. Tamkun |
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| Affiliation: | Department of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, California 95064 |
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| Abstract: | In this report, we investigate the mechanisms that regulate Drosophila histone H1 expression and its association with chromatin in vivo. We show that histone H1 is subject to negative autoregulation and exploit this result to examine the effects of mutations of the main phosphorylation site of histone H1. |
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| Keywords: | Drosophila histone H1 chromatin gene expression |
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