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Single-channel gating and regulation of human L-type calcium channels in cardiomyocytes of transgenic mice |
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| Authors: | Groner Ferdi Rubio Marta Schulte-Euler Patrick Matthes Jan Khan Ismail F Y Bodi Ilona Koch Sheryl E Schwartz Arnold Herzig Stefan |
| Affiliation: | Department of Pharmacology, University of Cologne, 50931, K?ln, Germany. |
| Abstract: | Overexpression of human cardiac L-type Ca(2+) channel pores (hCa(v)1.2) in mice causes heart failure. Earlier studies showed Ca(v)1.2-mRNA increase by 2.8-fold, but whole-cell current density enhancement by |
| Keywords: | Human cardiac L-type Ca2+ channel Transgenic mouse Single-channel |
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