Grabbing the cat by the tail: manipulating molecules one by one |
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| Authors: | Bustamante C Macosko J C Wuite G J |
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| Institution: | Howard Hughes Medical Institute, Berkeley, California, USA. carlos@alice.berkeley.edu |
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| Abstract: | Methods for manipulating single molecules are yielding new information about both the forces that hold biomolecules together and the mechanics of molecular motors. We describe here the physical principles behind these methods, and discuss their capabilities and current limitations. |
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