Affiliation: | From the ‡Department of Cellular Signaling and ;§21st Century Centers of Excellence Program “CRESCENDO,” Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba 6-3, Aramaki, Aoba-ku, Sendai 980-8578, Japan and ;¶The Vollum Institute, Oregon Health & Science University, Portland, Oregon 97239-3098 |