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Characterization of the metabolic shift between oxidative and fermentative growth in Saccharomyces cerevisiae by comparative 13C flux analysis
Authors:Oliver?Frick,Christoph?Wittmann  author-information"  >  author-information__contact u-icon-before"  >  mailto:c.wittmann@mx.uni-saarland.de"   title="  c.wittmann@mx.uni-saarland.de"   itemprop="  email"   data-track="  click"   data-track-action="  Email author"   data-track-label="  "  >Email author
Affiliation:1.Biochemical Engineering Institute,Saarland University,Saarbrücken,Germany
Abstract:

Background  

One of the most fascinating properties of the biotechnologically important organism Saccharomyces cerevisiae is its ability to perform simultaneous respiration and fermentation at high growth rate even under fully aerobic conditions. In the present work, this Crabtree effect called phenomenon was investigated in detail by comparative 13C metabolic flux analysis of S. cerevisiae growing under purely oxidative, respiro-fermentative and predominantly fermentative conditions.
Keywords:
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