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Up-regulation of thioredoxin interacting protein (Txnip) by p38 MAPK and FOXO1 contributes to the impaired thioredoxin activity and increased ROS in glucose-treated endothelial cells
Authors:Xiaonan Li  Yuanyuan Rong  Mei Zhang  Scott A LeMaire  Yun Zhang  Ying H Shen
Institution:a The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Public Health, Shandong University Qilu Hospital, Jinan, No. 107, Wen Hua Xi Road, Jinan, Shandong 250012, PR China
b Division of Cardiothoracic Surgery, The Michael E. DeBakey Department of Surgery, Baylor College of Medicine, BCM 390, One Baylor Plaza, Houston, TX 77030, USA
Abstract:
Keywords:p38 MAPK  FOXO1  Glucose  ROS  Thioredoxin interacting protein
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