Role of T cells in abscess formation |
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Authors: | Tzianabos Arthur O Kasper Dennis L |
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Institution: | Channing Laboratory, Brigham and Women's Hospital, Departments of Medicine, Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA. atzianabos@channing.harvard.edu |
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Abstract: | A series of recent studies have shed new light on the strategy used by certain bacterial pathogens to induce a classic infectious process: abscess formation. This work describes how zwitterionic polysaccharides on the surface of these organisms interact with the host immune system in general, and with T cells in particular, to coordinate this pathobiologic response. |
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