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c-FLIP Expression in Foxp3-Expressing Cells Is Essential for Survival of Regulatory T Cells and Prevention of Autoimmunity
Authors:Carlos Plaza-Sirvent  Marc Schuster  Yvonne Neumann  Ulrike Heise  Marina C Pils  Klaus Schulze-Osthoff  Ingo Schmitz
Institution:1. Systems-Oriented Immunology and Inflammation Research Group, Department of Immune Control, Helmholtz Center for Infection Research, Inhoffenstraße 7, 38124 Braunschweig, Germany;2. Institute of Molecular and Clinical Immunology, Otto-von-Guericke University, Leipziger Straße 44, 39120 Magdeburg, Germany;3. Mouse Pathology Platform, Helmholtz Center for Infection Research, Inhoffenstraße 7, 38124 Braunschweig, Germany;4. Interfaculty Institute for Biochemistry, University of Tübingen, Hoppe-Seyler-Str. 4, 72076 Tübingen, Germany;5. German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
Abstract:
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  • Keywords:apoptosis  c-FLIP  Cflar  regulatory T cell
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