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The hAPP‐YAC transgenic model has elevated UPS activity in the frontal cortex similar to Alzheimer’s disease and Down’s syndrome
Authors:Hyemyung Seo  Ole Isacson
Affiliation:1. Neuroregeneration Laboratories, Center for Neuroregeneration Research, McLean Hospital/Harvard Medical School, Belmont, MA, USA;2. Department of Molecular and Life Sciences, Hanyang University, Gyeonggi‐do, Korea
Abstract:
Keywords:amyloid precursor protein  cortex  patient  proteasome  transgenic mice  ubiquitin
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