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Differential modulation of mu‐opioid receptor signaling to adenylyl cyclase by regulators of G protein signaling proteins 4 or 8 and 7 in permeabilised C6 cells is Gα subtype dependent
Authors:Jeffery N Talbot  David L Roman  Mary J Clark  Rebecca A Roof  John J G Tesmer  Richard R Neubig  John R Traynor
Institution:1. Department of Pharmacology, University of Michigan, Ann Arbor, MI, USA;2. Department of Pharmaceutical and Biomedical Sciences, Raabe College of Pharmacy, Ohio Northern University, Ada, OH, USA;3. Present address: Division of Medicinal and Natural Products Chemistry, College of Pharmacy, University of Iowa, Iowa City, IA 52242, USA.;4. Present address: Division of Intramural Research, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892, USA.;5. Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA;6. Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA;7. Center for Chemical Genomics, University of Michigan, Ann Arbor, MI, USA;8. Substance Abuse Research Center, University of Michigan, Ann Arbor, MI, USA
Abstract:
Keywords:adenylyl cyclase    proteins  mu‐opioid  permeabilization  regulators of G protein signaling proteins
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