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A residue close to α1 loop F disrupts modulation of GABAA receptors by benzodiazepines while their binding is maintained
Authors:Roland Baur  Benjamin P. Lüscher  Lars Richter  Erwin Sigel
Affiliation:1. Institute of Biochemistry and Molecular Medicine, University of Bern, Bern, Switzerland;2. These authors contributed equally to this study.;3. Department of Medicinal Chemistry, University of Vienna, Vienna, Austria
Abstract:
Keywords:benzodiazepine binding  benzodiazepine modulation  channel gating  F loop  GABA  GABAA receptor
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